Plain-English translation of NCT07565727 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is trying to better understand why some pregnant people develop serious complications like preeclampsia or gestational diabetes. Instead of only looking at blood sugar (as is standard care), researchers want to study how your body processes different types of nutrients—fats, proteins, and sugars—and how your placenta responds to these changes. By learning more about these processes early in pregnancy, doctors hope to better prevent or manage these conditions.
Right now, doctors mainly screen pregnant people for gestational diabetes using one simple blood sugar test. However, researchers believe that looking at a wider range of metabolic changes—including how the body handles fats and other nutrients, and how the placenta adapts—could help identify and treat pregnancy complications much earlier, when intervention is most effective.
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You will attend study visits where researchers will collect blood samples, measure your body composition, and ask you to complete a 2-hour glucose tolerance test (a standard test during pregnancy where you drink a sugary liquid and have blood drawn). You will also complete surveys and possibly have other measurements taken. The study will track you and your baby's health throughout your pregnancy and after birth to understand how early metabolic changes connect to pregnancy complications.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
United States
Sponsor
University of Tennessee Graduate School of Medicine
Enrollment target
~50 participants
Started
December 2025
Primary completion
August 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 45 Years
Sex
Female only
Last updated on clinicaltrials.gov in May 2026.
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Central contact
Jill M Maples, PhD
University of Tennessee Graduate School of Medicine
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