Recruiting

Testing a new oral medication for obesity in adults

Plain-English translation of NCT07570758 on ClinicalTrials.gov ↗ · Source last updated June 2026 · Translation generated June 2026 · How we translate trials

Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.

What is this trial?

This is a Phase 2 clinical trial testing , an oral medication designed to help treat obesity. Researchers want to understand whether this medication is safe and well-tolerated when taken by mouth in adults with obesity. About half of participants will receive the real medication, and half will receive a placebo (a dummy pill with no active ingredient) to help determine if the medication actually works.

Obesity is a serious health challenge that affects millions of people, and current treatment options are limited. This trial is exploring whether this new medication could offer a safe and effective option for people struggling to manage their weight.

Do you qualify?

You likely qualify if…

you are between 18 and 60 years old
you have a BMI (body mass index) greater than 30 and less than 50
your weight has been stable for at least 3 months (with less than 5% change)
your diet and eating habits have been stable for at least 3 months
you are willing to follow study requirements and sign an informed consent form

You likely don't qualify if…

you have a severe or poorly controlled psychiatric condition, such as bipolar disorder or major depression, or a recent history of suicidal thoughts
you have a history of schizophrenia or schizoaffective disorder
you have or have had significant heart disease, heart failure, heart attack, or certain heart rhythm problems
you have current liver, kidney, lung, heart, or serious stomach disease
you have a history of blood clots or bleeding disorders

What participation looks like

If you qualify and join, you'll be randomly assigned to take either the new medication or a placebo by mouth. You'll attend study visits where researchers will check your safety through blood tests, heart rhythm monitoring, and other assessments. The trial will carefully track how your body responds to the treatment and monitor for any side effects throughout the study period.

AI-generated summary from trial data · Jun 28, 2026 · Not medical advice

Trial locations(3 sites)

United States

Monroe Biomedical Research, Louisville, Kentucky

Monroe Biomedical Research, Monroe, North Carolina

Monroe Biomedical Research, North Charleston, South Carolina