Plain-English translation of NCT07571889 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a simple numbing spray — a cotton pad soaked with lidocaine (a numbing medicine) — placed in your nostrils for 5 minutes can make onabotulinumtoxinA injections for chronic migraine less painful. People who get this medication often find the injections uncomfortable, so this study is looking for an easy way to reduce that discomfort during your regular treatment appointments.
Many people find the injections needed for this medication uncomfortable and painful, which can make them hesitant to continue treatment. Researchers want to see if a simple, inexpensive numbing spray used before the injections could make the experience more tolerable and help people stick with their migraine treatment.
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During this crossover study, you would participate in two separate injection sessions scheduled for your regular migraine treatment. Before one session, you'll receive a cotton pad soaked in numbing medicine placed in each nostril for 5 minutes; before the other session, you'll receive a cotton pad soaked in salt water (placebo) — neither you nor the researchers will know which is which. You'll rate your pain during and after each injection appointment, allowing researchers to compare whether the numbing treatment made a difference for you.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States