Recruiting

Testing a new injectable medication for weight and diabetes management

Plain-English translation of NCT07578584 on ClinicalTrials.gov ↗ · Source last updated June 2026 · Translation generated June 2026 · How we translate trials

Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.

What is this trial?

This is a Phase 1 clinical trial testing a new medication called , which is given as a weekly injection under the skin. The study will determine whether this medication is safe, well-tolerated, and effective in three groups: healthy people, people with overweight or obesity, and people with type 1 diabetes who also have overweight or obesity. Researchers will track how your body processes the medication and how it affects your weight and metabolism.

Current treatment options for weight management and type 1 diabetes are limited. This study explores whether this new treatment could offer an additional option for people struggling with weight, especially those living with type 1 diabetes.

Do you qualify?

You likely qualify if…

you are between 18 and 55 years old
you are generally healthy (if enrolling in the first group) or have overweight/obesity (if enrolling in later groups)
you have been diagnosed with type 1 diabetes for at least one year (if enrolling in the type 1 diabetes group)
you have been using insulin injections consistently for at least 90 days (if enrolling in the type 1 diabetes group)
you are able and willing to follow the study protocol and attend all scheduled visits

You likely don't qualify if…

you are taking other prescription medications or herbal products (within 14 days of starting the study)
you have a history of heart, kidney, liver, or digestive system problems
you have diabetes or blood sugar control issues (if enrolling in the healthy or overweight groups)
you are unwilling or unable to stop using certain medications before the study begins
you are a woman of childbearing potential (women must be post-menopausal or unable to have children)

What participation looks like

You will visit the research clinic multiple times over approximately 29 weeks for screening, treatment, and follow-up visits. During the study, you will receive either the new medication or a placebo (inactive injection) once per week as a shot under your skin. You will have blood tests, physical exams, and other routine health checks to monitor your safety and how your body responds to the treatment. The study team will carefully watch for any side effects and track changes in your weight and metabolic health.

AI-generated summary from trial data · Jun 16, 2026 · Not medical advice

Trial locations(1 site)

Germany

Profil Institut für Stoffwechselforschung GmbH, Neuss