Plain-English translation of NCT07579650 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a procedure called a serratus posterior superior intercostal plane block, which is an ultrasound-guided injection of numbing medication near nerves in the chest wall. The goal is to see whether this injection, given before your mastectomy surgery, can reduce your pain and how much pain medication you need after the operation.
After breast surgery, many patients experience significant pain that can lead to high doses of opioid medications and their side effects. This trial exists to find out whether this newer nerve block technique can be an effective way to manage pain without relying so heavily on strong opioids.
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You will be randomly assigned to receive either the nerve block injection with numbing medication or a placebo (saltwater) injection that looks identical—neither you nor the research team will know which one you received. Before your surgery, you will receive this injection under ultrasound guidance, plus standard anesthesia. After surgery, the research team will monitor your pain levels and how much pain medication you need, and you will rate your pain using a simple numbered scale.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
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