Complete advanced eye scans to help researchers understand glaucoma types

What is this trial?

This research study uses two types of advanced eye imaging—OCT and OCTA—to take detailed pictures of the back of the eye in people with different types of glaucoma and in healthy volunteers. The study aims to understand how glaucoma changes the eye's blood vessels and the tissue layers underneath, which could help doctors diagnose and manage glaucoma better in the future.

Glaucoma is a serious eye disease that can cause blindness if not caught and treated early. While doctors have good imaging tools available, researchers want to understand more about how different types of glaucoma affect the eye's blood supply and deeper structures—information that could lead to better, earlier detection and treatment.

Do you qualify?

You likely qualify if…

you are between 18 and 90 years old
you have been diagnosed with one type of glaucoma (angle-closure disease or open-angle glaucoma) by a glaucoma specialist, OR you are healthy with no eye disease
you have not had eye surgery, or only minor eye surgery in the past
your eye pressure is normal or well-controlled (if you have glaucoma)

You likely don't qualify if…

you have a history of retinal disease, such as macular degeneration, diabetic eye disease, or retinal vein occlusion
you have optic nerve damage from causes other than glaucoma, such as multiple sclerosis
you are unable to cooperate with eye imaging because of other health conditions
you are unwilling or unable to sign the informed consent form

What participation looks like

If you join this study, you will visit the research center for eye imaging appointments where trained technicians will use two types of non-invasive cameras to take detailed pictures of your eyes. The imaging is painless and similar to getting your eyes photographed; the whole process typically takes less than an hour. Depending on which group you are in (healthy volunteer or glaucoma patient), you may be asked to return for follow-up visits so researchers can track any changes over time.

Eye imaging study comparing angle-closure and open-angle glaucoma

What is this trial?

Do you qualify?

What participation looks like

Trial locations(1 site)