Plain-English translation of NCT07581145 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This pilot study is testing whether semaglutide, a medication already used to treat type 2 diabetes, can help foot ulcers heal faster and better. Researchers will compare people who receive semaglutide to those who receive a placebo (a fake injection) over 20 weeks. The hope is to learn whether this medication might offer a new way to help diabetic foot ulcers heal.
Foot ulcers are a serious complication of type 2 diabetes that can be slow to heal and lead to infection or amputation. Researchers want to see if this medication, which already helps control blood sugar and has other beneficial effects on the body, might also improve wound healing.
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If you join this study, you will receive either the medication or a placebo as a weekly injection under your skin. You will start with a low dose that gradually increases over 8 weeks, depending on how well you tolerate it. You'll need to visit the clinic every week for 20 weeks so researchers can measure how your ulcer is healing and check for any side effects.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
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