Plain-English translation of NCT07583823 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether increasing the pacing rate on your existing pacemaker can help you feel better and exercise more easily if you have cardiac amyloidosis. The research team will adjust your pacemaker to a personalized faster rate based on your height and heart function, then measure how your heart failure symptoms and ability to exercise change before and after this adjustment.
Many people with cardiac amyloidosis struggle with heart failure symptoms and limited exercise tolerance, even with current treatments. This study wants to see if simply adjusting an existing pacemaker to a higher rate — without adding new medication — might help relieve these symptoms.
You likely qualify if…
You likely don't qualify if…
You would visit the cardiac amyloidosis clinic where your pacemaker would be reprogrammed to a personalized faster rate based on your individual heart measurements. The study team would then track your heart failure symptoms and measure your exercise ability before and after this pacemaker adjustment to see if the higher pacing rate helps you feel better and exercise more comfortably.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
United States
Sponsor
University of Minnesota
Enrollment target
~10 participants
Started
October 2025
Primary completion
October 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Meghan Muscala
University of Minnesota
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.