Plain-English translation of NCT07586904 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This early-stage trial is testing a combination of two medications — cadonilimab and high-dose interferon — given before surgery to treat advanced melanoma. The study wants to see if this combination can shrink tumors and help the body's immune system fight the cancer more effectively. Researchers will also track how safe the treatment is and what side effects patients experience.
Advanced melanoma is a serious form of skin cancer that often spreads to lymph nodes or other parts of the body. This trial is exploring whether giving this medication combination before surgery might help more patients achieve better outcomes and prepare the body to fight remaining cancer cells.
You likely qualify if…
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You would receive the two medications through injections or infusions before having surgery to remove your melanoma. The study is very small — only 10 people total — and is designed to gather initial safety and effectiveness information. You'll have regular visits for blood tests, physical exams, and imaging scans to monitor how you're responding to the treatment and check for any side effects.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
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