Plain-English translation of NCT07594821 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Carpal tunnel syndrome causes pain and numbness in the hand and wrist. Most patients improve with surgery that releases pressure on the median nerve at the wrist. However, some people continue to have symptoms after surgery. This trial is testing whether releasing pressure at a second location in the forearm — in addition to the wrist — helps patients feel better and have fewer lasting symptoms.
About 4 in 10 patients still experience pain and numbness even after standard carpal tunnel surgery. Doctors think some of these patients may have pressure on the nerve in the forearm as well, which isn't being treated. This trial wants to find out whether releasing pressure in both locations gives patients better long-term results.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive one of two types of surgery: standard carpal tunnel release at the wrist, or carpal tunnel release combined with release of tissue in your forearm. The study will track your symptoms and hand function after surgery to compare how well each approach works. You'll likely complete follow-up visits and questionnaires to report how you're feeling over time.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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