Recruiting

Test a new computer-based memory assessment for early Alzheimer's disease

Plain-English translation of NCT07598617 on ClinicalTrials.gov ↗ ·

What is this trial?

This trial is testing a new computerized cognitive assessment tool designed to detect very early signs of Alzheimer's disease. The study aims to evaluate whether this computer-based memory test is sensitive enough to catch the subtle cognitive changes that happen before dementia symptoms develop. The tool will be tested in people aged 65 and older who have noticed changes in their memory or thinking abilities.

Currently, most cognitive tests available in the NHS are not sensitive enough to detect the very early, subtle memory and thinking changes that occur in preclinical Alzheimer's disease. This study exists to develop and evaluate a better screening tool that, combined with blood biomarkers, could help doctors diagnose Alzheimer's disease earlier—potentially before dementia develops—so that new disease-slowing medications can be started sooner.

Do you qualify?

You likely qualify if…

you are 65 years or older
you have noticed changes in your memory or thinking abilities within the last 5 years
you score within a certain range on memory screening questionnaires
English is your first language
you have normal performance on standard cognitive tests (for those with subjective memory concerns only)

You likely don't qualify if…

you have been diagnosed with dementia
you have had a previous stroke, traumatic brain injury, or other neurological condition affecting the brain
you have severe depression or current serious mental health conditions like schizophrenia or bipolar disorder
you have untreated sleep apnea or current substance abuse issues
you have sensory impairments (such as blindness) that cannot be corrected with aids

What participation looks like

If you qualify, you would take part in this research study focused on evaluating the new computerized memory assessment tool. You would complete the computer-based cognitive test, which is designed to be more sensitive to early memory changes than traditional tests. The study involves 120 participants with either subjective memory concerns or mild cognitive impairment, and you would be part of helping researchers understand whether this new tool is effective at detecting very early Alzheimer's disease.

Test a new computer-based memory assessment for early Alzheimer's disease

What is this trial?

Do you qualify?

What participation looks like

Trial locations(3 sites)