Plain-English translation of NCT07600580 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Thyroid Cancer research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether a technique called a bilateral intermediate cervical plexus block—an injection that numbs nerves in the neck—can reduce your body's stress response during thyroid removal surgery. Half of the participants will receive standard anesthesia alone, while the other half will receive standard anesthesia plus the nerve block injection. Researchers will measure stress-related substances in your blood and saliva to see if the nerve block makes a difference.
Thyroid surgery can trigger a significant stress response in your body, which can affect how you feel after the operation. This treatment might reduce that stress response and potentially help you recover better, but researchers need to study whether it actually works.
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You will be randomly assigned to either the standard anesthesia group or the standard anesthesia plus nerve block group. If you're in the nerve block group, you'll receive an injection of numbing medication in your neck before surgery begins. During and after your thyroid surgery, doctors will collect saliva and blood samples to measure how your body responds to the procedure. You'll be followed after surgery, and you won't be told which group you were in until after your recovery period is complete.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
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