Plain-English translation of NCT07601464 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying tiny molecules called microRNAs that circulate in your blood and appear in liver tissue to see if they can predict how well heat ablation treatment will work for your liver cancer. Heat ablation (also called thermal ablation or radiofrequency ablation) is a procedure that uses heat to destroy cancer cells. By identifying these biological markers before and after treatment, doctors hope to eventually personalize care and better predict which patients will benefit most.
Not all patients respond equally well to heat ablation treatment for liver cancer, and doctors currently have limited ways to predict who will benefit most. This study aims to discover blood and tissue-based markers that could help identify treatment response early and guide personalized treatment decisions in the future.
You likely qualify if…
You likely don't qualify if…
You will undergo the heat ablation treatment your doctor has already recommended for your cancer. As part of this study, you will have blood samples taken and may have a small piece of liver tissue collected before and after your treatment. Researchers will analyze these samples to look for microRNAs and other markers that might help predict how well the treatment worked for you. The study involves approximately 150 patients total and will help build knowledge for better personalized cancer care in the future.
AI-generated summary from trial data · Jul 9, 2026 · Not medical advice
Italy
Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Enrollment target
~150 participants
Started
March 2026
Primary completion
December 2028
Age range
18 Years – 64 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Andrea Boccatonda, MD
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.