Plain-English translation of NCT07601646 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new medication called , a paste containing alprostadil that is applied inside the urethra to help improve erectile function. The medication works by relaxing blood vessels and increasing blood flow to help men achieve erections. Researchers will test three different dose levels over 12 weeks to find the right amount that works best, and some participants may also take sildenafil (Viagra) alongside the treatment.
Many men with erectile dysfunction don't respond well to oral pills like Viagra or have tried other treatments without success. This trial exists to develop a new treatment option that works differently—by delivering the active medication directly where it's needed—for men who need alternatives.
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You will visit the study clinic multiple times over 12 weeks and receive up to 11 applications of the medication paste inside the urethra. The study starts with a lower dose and may increase to higher doses based on how well the treatment works and how you tolerate it. You may also take an oral medication (sildenafil) alongside the paste treatment at some visits, and you'll complete questionnaires and exams to measure whether your erectile function improves.
AI-generated summary from trial data · Sep 20, 2026 · Not medical advice
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