Plain-English translation of NCT07602387 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing capsaicin 8%, a cream made from hot peppers, to treat chronic nerve pain in the legs caused by cancer chemotherapy drugs called taxanes. Researchers will apply the medication to your skin multiple times over a year and take small skin samples to understand how the treatment works and whether it helps reduce your pain.
Nerve pain from chemotherapy is a serious side effect that can last long after cancer treatment ends, and many patients don't respond well to current pain medications. This study aims to see whether this medication might offer relief and to understand the biological changes that happen when it works.
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You will receive applications of the capsaicin cream to your lower legs at least 5 times over approximately one year, with at least 60 days between applications (though this may be adjusted based on how you respond). Before your first application and at several points during the year, you'll have small skin samples taken (skin biopsies) to help researchers understand how the treatment is affecting your nerve fibers. You'll also have eye imaging, nerve function tests, and pain assessments at various visits.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
France