Plain-English translation of NCT07605728 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial tests whether a special probiotic supplement (containing beneficial bacteria and plant compounds) can help reduce belly discomfort and diarrhea in breast cancer patients taking Abemaciclib. Abemaciclib is an effective targeted therapy that prevents breast cancer from coming back, but it commonly causes digestive side effects that don't always improve with standard anti-diarrhea medication. Researchers want to see if this supplement can help restore balance in your gut and make you feel better.
Many breast cancer patients experience ongoing stomach discomfort while taking this medication, even when using standard treatments. This trial exists to find a natural way to help ease these side effects and improve quality of life during cancer treatment.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive either the probiotic supplement or a placebo first, then switch to the other halfway through. The study lasts 4 months total. You'll continue taking your regular Abemaciclib and can use standard anti-diarrhea medication whenever you need it. Researchers will ask you about your symptoms and take blood samples to check your overall health and see if the supplement helps your metabolism.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
Taiwan