Plain-English translation of NCT07612891 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is one of the first times this treatment has been tested in people.
This is an early-stage clinical trial testing a new drug called for adults with advanced breast cancer or other solid tumors that have grown despite standard treatment. The trial is split into two phases: first, researchers will test different doses to find the safest amount, and then they will give that dose to more patients to see if the medication actually helps shrink tumors. Researchers will also measure how your body processes the medication and watch carefully for any side effects.
Many patients with advanced hormone-receptor-positive breast cancer and other solid tumors run out of effective treatment options, or their cancer stops responding to standard therapies. This medication may offer a new way to fight these cancers by targeting specific cancer cell processes that haven't been treated this way before.
You likely qualify if…
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In Phase 1, you will receive at a starting dose, and researchers will gradually increase doses in small groups of patients to find the safest amount. In Phase 2, more patients will receive the safest dose identified in Phase 1. You will have regular visits for physical exams, blood tests, and scans to check if your tumors are shrinking and to monitor for any side effects. The trial involves careful tracking of how your body responds to the medication over time.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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