Plain-English translation of NCT07616128 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Migraine research guide โPhase 2 โ Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether EVO756, a new medication taken by mouth once daily, can help prevent migraines in adults. The study will compare two different doses of this medication against a placebo (a pill with no active ingredient) to see which works best and is safe. About 330 people will participate, and researchers will track how often and how severe migraines occur over time.
Many people with migraines don't respond well to existing preventive medications, leaving them without good options to reduce how often migraines happen. This trial is testing whether this new treatment could help people whose previous preventive therapies haven't worked.
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If you join, you will be randomly assigned to take either one of two doses of the medication or a placebo pill once daily. You'll take your assigned pill every day throughout the study and keep track of your migraines in a log or diary. You'll have regular visits with the research team to report how you're doing, discuss any side effects, and let them know whether your migraines are improving.
AI-generated summary from trial data ยท Jul 13, 2026 ยท Not medical advice
United States