Plain-English translation of NCT07625020 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a procedure called nerve hydrodissection can help people with diabetes who have compressed nerves in their legs. The procedure involves using ultrasound to guide an injection of mecobalamin and saline around the compressed nerve to free it from surrounding tissue. Researchers will compare people who receive the actual treatment to those who receive a sham (fake) procedure to see if the real treatment improves nerve function, reduces pain, and improves quality of life.
People with diabetes often develop compressed nerves in their legs that cause numbness, pain, and weakness. Many patients don't respond well enough to medications alone, so researchers are testing whether this minimally invasive injection procedure could provide relief.
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You will have four in-person visits over about one month. At your second visit, you will receive either the nerve hydrodissection injection or a sham procedure—you won't know which one. During the visits, you'll undergo nerve ultrasound scans, complete questionnaires about your symptoms and quality of life, and the doctors measuring your results won't know which treatment you received. You will continue taking your regular diabetes and nerve medications throughout the study.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
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