Plain-English translation of NCT07626710 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is collecting information from patients who are undergoing a minimally invasive procedure called trans-catheter aortic valve implantation (TAVI) to replace a narrowed aortic valve. Researchers want to understand how the contrast dye used during heart imaging tests and the valve procedure itself affects kidney function, and whether any kidney changes affect patient outcomes over the following year.
When doctors use contrast dye to take detailed images of your heart and blood vessels, this dye can sometimes stress the kidneys, especially in people who already have kidney problems or are having multiple procedures. This study aims to learn how often this happens with this minimally invasive valve replacement procedure and whether it affects patients' health and survival over time.
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If you join this registry, you will receive the minimally invasive valve replacement procedure that your doctor has already recommended — this study does not add any new procedures. However, researchers will carefully track your kidney function by measuring it several times during the week after your procedure and your initial imaging tests, then follow up on your health and survival status one year after your valve replacement. Your anonymized medical information will be collected and analyzed as part of a large registry of patients undergoing this procedure.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Italy
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Enrollment target
~1,000 participants
Started
August 2024
Primary completion
August 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
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Central contact
Enrico Romagnoli, MD, PhD
Fondazione Policlinico Universitario Agostino Gemelli
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