Plain-English translation of NCT07628751 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The SOCRATES trial is testing whether a focused radiation therapy technique called SABR (stereotactic ablative radiotherapy) works better than current standard treatments for early-stage liver cancer. Participants will be randomly assigned to receive either SABR or one of several standard care options, which may include thermal ablation, chemotherapy delivered through the blood vessels, or radioactive material delivered through the blood vessels. The trial will measure how well each treatment works, how safe it is, and how it affects quality of life.
Early-stage liver cancer can be difficult to treat, especially when surgery isn't an option. Doctors want to know whether this newer radiation therapy approach might be more effective, safer, or easier on patients than the treatments currently available.
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If you join this trial, you will be randomly placed into one of two groups. One group will receive SABR (a focused form of radiation therapy delivered over a few sessions), and the other will receive standard care as recommended by your doctor's team. You will have regular follow-up visits to check how well the treatment is working, monitor for any side effects, complete quality-of-life questionnaires, and have imaging scans to track your cancer. The trial involves about 218 participants total, and your doctor will discuss the specific schedule and what to expect based on which treatment you receive.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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