Plain-English translation of NCT07636343 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a specialized form of strength training — called eccentric muscle training — can help people with heart failure with reduced ejection fraction build muscle and improve their physical fitness. The study compares this new approach to traditional cardiac rehabilitation exercise. Researchers believe this method might be easier on the heart while still building more strength and muscle mass.
Many people with heart failure struggle to complete standard exercise programs because they become tired easily and may have other health conditions. This trial exists to see if the new training approach allows patients to work harder without straining their hearts as much, potentially leading to better strength, muscle, and overall fitness.
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You would attend 45 supervised exercise sessions over several weeks. Half of participants would do the specialized eccentric strength training combined with cardiovascular exercise, while the other half would do traditional cardiac rehabilitation. Before, during, and after the program, researchers would measure your muscle strength, muscle mass, heart fitness, and overall physical function through standard tests.
AI-generated summary from trial data · Aug 12, 2026 · Not medical advice
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