Plain-English translation of NCT07638254 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether buffered local anesthesia — a numbing medicine that has been specially prepared by adding sodium bicarbonate to improve how well it works — reduces pain and anxiety better than the standard numbing medicine used in dentistry. Researchers will compare the two types of numbing medicine in school-aged children who need dental treatment for pulpitis, which is an infection of the inner part of the tooth. The study will measure how much pain and anxiety children experience during their procedure using behavioral observations, heart rate monitoring, and pain rating scales.
Dental pain and anxiety in children can make treatment difficult and create lasting negative feelings about dental care. This trial exists to see whether buffering the numbing medicine — a simple preparation change — could make it work faster and more effectively, helping children have a better and less stressful experience.
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You will visit a dental clinic where you'll receive either the buffered or standard numbing medicine before your tooth treatment (pulpotomy or pulpectomy). During the procedure, researchers will monitor your heart rate, skin responses, and pain level using observation scales and simple pain rating tools. They will also record how quickly the numbing medicine starts working and how long it lasts, and they'll follow you through recovery to ensure the numbness wears off normally.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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