Plain-English translation of NCT07649408 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study looks at how new Crohn's disease medications affect your sleep. Researchers know that sleep problems and inflammation are connected—poor sleep can make inflammation worse, and inflammation can disrupt sleep. This trial will use a Fitbit watch to objectively measure your sleep quality while you start one of several advanced treatments (such as anti-TNF therapy, vedolizumab, ustekinumab, IL-23 inhibitors, JAK inhibitors, or S1P inhibitors) as part of your routine medical care.
While these newer medications help reduce inflammation and improve quality of life for many Crohn's patients, sleep disturbances remain a common problem that doctors don't fully understand. This trial exists to better understand the relationship between the medication and sleep, so doctors can help patients sleep better during treatment.
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You would wear a Fitbit watch while you sleep to track your sleep patterns objectively. You would also complete questionnaires about your sleep quality and how you're feeling. This happens as you start your new Crohn's medication as part of your regular medical care—the study doesn't require additional treatment visits beyond what your doctor would normally do. The study involves about 30 patients total.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
Israel
Sponsor
Shmuel Kivity, MD
Enrollment target
~30 participants
Started
August 2025
Primary completion
October 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
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