Plain-English translation of NCT07657403 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two surgical approaches for brain tumors located in areas that control important functions like speech, movement, and thinking. One group will receive surgery guided by connectome-guided navigation—a newer technique that uses detailed brain mapping before and during surgery to help doctors remove the tumor while protecting critical brain functions. The other group will receive standard surgery guided by conventional brain imaging techniques.
Brain tumors in areas that control speech, movement, or thinking are very challenging to treat because doctors must remove as much tumor as possible while avoiding damage to these vital functions. This trial exists to see whether the new mapping technology can help surgeons do both better—removing more tumor while preserving your ability to speak, move, and think.
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If you enroll, you will be randomly assigned to either the advanced brain mapping surgery group or the standard surgery group. Before surgery, you will have special imaging scans (including detailed brain mapping scans) to help plan your operation. During surgery, your surgical team will use either advanced computer-guided navigation with real-time brain monitoring or standard surgical guidance, depending on which group you are in. After surgery, you will have follow-up visits to check your recovery and measure how well your brain functions have been preserved.
AI-generated summary from trial data · Jul 6, 2026 · Not medical advice
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