Plain-English translation of NCT07657845 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is tracking young patients who had a procedure called percutaneous intercostal cryoneurolysis—a technique that freezes nerves in the chest wall before surgery to reduce pain after a procedure called the Nuss operation. Researchers want to understand whether this nerve-freezing treatment is safe over the long term, how it affects pain, and how sensation in the chest returns to normal over time.
Chest wall surgery can cause significant pain during recovery, and doctors are looking for ways to manage that pain better. This study will help doctors understand whether this nerve-freezing approach is a safe and effective option for reducing pain and improving quality of life in young patients.
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You will visit the hospital at five scheduled timepoints—at 1, 3, 6, 12, and 24 months after your surgery. At each visit, doctors will perform a physical exam and test how your chest sensation is recovering. You'll also complete questionnaires about any pain you're experiencing and how the treatment has affected your quality of life. The study lasts two years total and helps researchers track your long-term recovery and safety.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Italy
Sponsor
Papa Giovanni XXIII Hospital
Enrollment target
~50 participants
Started
February 2025
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
14 Years and older
Last updated on clinicaltrials.gov in June 2026.
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Central contact
Stefano Mariconti, MD
Department of Anesthesia and Intensive Care, Paediatric Anesthesiology and Intensive Care Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.