Plain-English translation of NCT07660380 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether , a newer pain medication, causes less coughing than when given intravenously at the beginning of surgery. Some patients cough uncontrollably when is injected quickly, and researchers believe the medication might work differently in your body to prevent this reaction. The study will compare how often each medication causes coughing during the first two minutes after injection.
When is injected rapidly during anesthesia, it can trigger an unexpected coughing reflex in patients—an unwanted side effect that doctors currently try to prevent by adding extra medications. This trial exists to find out whether the new medication might prevent coughing from happening in the first place, rather than just treating it after it occurs.
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You would arrive for your scheduled surgery and be randomly assigned to receive one of two pain medications as a quick injection into your vein at the start of anesthesia. Medical staff would watch you closely for two minutes to count whether you cough, then complete your anesthesia with additional medications and proceed with surgery as planned. Your participation in the study ends once your surgery begins—the main part of the research is simply observing and recording whether coughing occurs after that initial injection.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
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