Plain-English translation of NCT07660445 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a combined approach using two endoscopic procedures—both performed during the same session—to help people with obesity and type 2 diabetes. The first procedure, called endoscopic sleeve gastroplasty (ESG), reduces stomach size to help you feel fuller faster. The second procedure, called pulsENDO, uses electrical pulses in the small intestine to help improve how your body handles blood sugar. Researchers are studying whether doing both procedures together is safe and effective over 2 years.
Many people struggle to manage both obesity and type 2 diabetes with diet, exercise, and medication alone. This trial exists to see whether combining two minimally invasive endoscopic procedures might offer a new treatment option that addresses both conditions at the same time, without requiring major surgery.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo both endoscopic procedures during a single session—performed through your mouth by a specialist, without major surgery. After the procedures, you will return for follow-up visits over 2 years so the research team can monitor your weight, blood sugar levels, and overall health. These visits will likely include blood tests, physical exams, and questions about how you're feeling and any changes in your symptoms.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Hong Kong
Sponsor
Chinese University of Hong Kong
Enrollment target
~20 participants
Started
August 2026
Primary completion
July 2029
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stephen Ng
Prince of Wales Hospital, the Chinese University of Hong Kong
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.