Plain-English translation of NCT07660458 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research investigates an important question: when parents of children with recurrent medulloblastoma (a serious brain tumor) experience depression, anxiety, or stress, does it affect whether their child completes prescribed cancer treatments? The study will follow 450 families over 12 months to understand how parental emotional health connects to treatment adherence.
Children with recurrent medulloblastoma need complex, long-term treatments to survive, and parents are responsible for making sure their children follow these regimens. However, the emotional burden on parents—fear, grief, anxiety—may make it harder for them to manage these demanding treatments. No one has studied whether parental distress directly predicts how well families stick to treatment plans for this rare, aggressive tumor.
You and your child would enroll together as a parent-child pair. At the start, you would complete questionnaires about your emotional well-being, including questions about depression, anxiety, stress, and trauma. Over the next 12 months, the researchers would monitor your child's treatment adherence using electronic medication caps (devices that track when medication bottles are opened), clinic attendance records, and your own medication logs. You may be asked to complete follow-up questionnaires during this period. The study is observational—meaning researchers are watching and measuring, not testing a new medication or treatment.
AI-generated summary from trial data · Aug 31, 2026 · Not medical advice
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