Freezing versus electrical nerve treatment for knee arthritis pain

This study is testing three different ways to reduce knee arthritis pain by targeting the nerves that carry pain signals. One approach freezes the nerves, while the other two use electrical energy — one with pulses and one with cooled energy — to reduce pain signaling. The trial will compare which method works best for people whose knee pain hasn't improved with standard treatments like pain pills or therapy.

Many people with knee arthritis don't get enough relief from oral pain medications or physical therapy, and they may not be able to afford or access injectable treatments. This trial is testing whether these minimally invasive nerve treatments could be a better option for managing pain in people with hard-to-treat knee arthritis.