Plain-English translation of NCT07671235 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
If your ACL (a ligament in your knee) fails after reconstruction surgery, you may need a second operation. This study is comparing two different graft options—tissue from your own body versus donor tissue—to see which one helps your knee heal better and last longer after revision surgery.
Repeat ACL surgery is trickier than the first time and often has higher failure rates. Doctors don't yet know which type of graft is best for these second surgeries, so this study aims to find out which approach gives patients the best outcomes and the strongest, most stable knees.
You likely qualify if…
You likely don't qualify if…
You will undergo revision ACL reconstruction surgery using one of two graft types chosen by your surgeon. After surgery, you will attend follow-up appointments over at least two years where doctors will examine your knee stability, assess your function and ability to return to activities, and possibly perform imaging tests to check on healing and rule out arthritis development.
AI-generated summary from trial data · Aug 29, 2026 · Not medical advice
Italy
Enrollment target
~150 participants
Started
July 2026
Primary completion
May 2027
Age range
18 Years – 50 Years
Last updated on clinicaltrials.gov in August 2026.
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Central contact
stefano zaffagnini
Stefano Zaffagnini
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.