Plain-English translation of NCT07680283 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When Crohn's disease affects the end of the small intestine, surgery to remove the diseased part is sometimes necessary. This trial is testing whether using ultrasound imaging during the operation helps surgeons choose healthier tissue to cut, compared to the current standard method of using their eyes and hands to decide where to cut. The goal is to see if this imaging-guided approach leads to better outcomes and fewer disease recurrences after surgery.
Even after surgery removes the diseased bowel, Crohn's disease often comes back in the same area. Doctors wonder if choosing resection margins—the edges of healthy tissue where the surgeon cuts—more carefully using ultrasound imaging might reduce this recurrence rate and improve long-term outcomes.
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If you enroll, you will have surgery to remove the diseased bowel section at Cleveland Clinic. You'll be randomly assigned to one of two groups: one group will have the surgeon use ultrasound imaging to help select the cutting margins, while the other group will use the standard visual and tactile method. After surgery, you'll have follow-up visits including endoscopy (a camera exam of your bowel) at set time points to check for disease recurrence. The study team will also review your surgical pathology (tissue samples) and collect information about your recovery and any complications.
AI-generated summary from trial data · Sep 1, 2026 · Not medical advice
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