Plain-English translation of NCT07680725 on ClinicalTrials.gov ↗ ·
This trial is testing whether a specific breathing exercise called bottle-PEP (positive expiratory pressure) can help people with Parkinson's disease strengthen their breathing muscles and improve their balance. The bottle-PEP exercise uses a simple homemade device—a plastic bottle filled with water—that you breathe against to build strength. Researchers want to see if this exercise, done at home for 8 weeks, works better than standard breathing exercises when added to regular Parkinson's rehabilitation.
People with Parkinson's disease often have weakness in their breathing muscles and balance problems that affect their quality of life. This study explores whether a low-cost, easy-to-do breathing exercise might help address these problems alongside standard care.
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You will join one of two groups: both groups will do standard Parkinson's rehabilitation, but one group will also do regular breathing exercises while the other group will do the bottle-PEP exercise. You'll do your assigned exercises at home 5 days a week for 8 weeks, performing 25 forced expirations (strong breaths out) using the bottle-PEP device. A researcher will teach you how to do the exercises during an initial visit and then check in with you weekly via video call to make sure you're doing them correctly. You'll be tested at the start, at week 8, and again 8 weeks after you finish the program.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Turkey (Türkiye)