Plain-English translation of NCT07682311 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing the Percept neurostimulator device, a brain implant that can automatically adjust the strength of electrical stimulation throughout the day in response to your brain's changing needs. Instead of delivering the same constant stimulation all day and night, this adaptive approach aims to better match your symptoms as they fluctuate, potentially reducing times when you feel under- or over-stimulated. The study will compare how well this smart adjustment works compared to your current standard stimulation settings.
Many people with Parkinson's disease find that standard brain stimulation doesn't adequately control their symptoms throughout the entire day — they may feel too stimulated at some times and not enough at others. This trial exists to see whether allowing the device to automatically sense your brain activity and adjust the stimulation in real-time can better manage these daily ups and downs.
You likely qualify if…
You likely don't qualify if…
You will wear your brain stimulation device in a special research mode at home for 40 to 60 days. During the day, you'll randomly receive either your standard constant stimulation or the new adaptive stimulation (in alternating blocks lasting 1 to 7 days), and you won't know which one is active each day. At night, you'll use your regular constant stimulation. You'll also need to attend study visits where researchers will test your device, monitor how you're doing, and assess your symptoms. The study involves blinded testing, meaning neither you nor some of the study staff will know which stimulation setting is active on any given day.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
United States