Plain-English translation of NCT07682961 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether a combination of three medications called , , and — given as injections every 6 months — works as well as a different two-medication injection given every 8 weeks. Both treatments are designed for people whose HIV is already well-controlled on daily oral medications, offering the possibility of switching to less frequent injections instead.
Many people with HIV who are doing well on daily pills would prefer fewer doses or injections. This study is testing whether the new medication combination can keep HIV suppressed with injections given only twice a year instead of every 8 weeks, making treatment simpler and easier to stick with.
You likely qualify if…
You likely don't qualify if…
If you join, you'll be randomly assigned to receive either injections every 6 months or every 8 weeks for one year (52 weeks). The first injections involve an oral dose plus IV infusions and a subcutaneous injection on day one, followed by maintenance injections on your assigned schedule. You'll have regular clinic visits to check your HIV levels and monitor how well the treatment is working, and you'll have the option to continue in an extension phase after the first year.
AI-generated summary from trial data · Aug 23, 2026 · Not medical advice
United States