Plain-English translation of NCT07687576 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
The CAPTURE AMI trial is testing whether a procedure called sustained mechanical thrombectomy—which physically removes blood clots from heart arteries—works better than standard treatment alone for patients having a heart attack with a large clot burden. You would be randomly assigned to receive either standard treatment or standard treatment combined with the clot-removal procedure.
When patients have a heart attack caused by a large blood clot, doctors want to know if actively removing the clot before placing a stent (a small tube to keep the artery open) leads to better outcomes than standard care alone.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be randomly assigned to one of two groups during your emergency heart attack treatment. Both groups will receive standard care with imaging guidance (a special type of scan called OCT). One group receives standard treatment alone, while the other group also receives the mechanical clot-removal procedure before the stent is placed. The trial focuses on measuring how much clot remains after treatment.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
United Kingdom