Plain-English translation of NCT07688720 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing transcutaneous auricular neurostimulation (tAN), a treatment that uses gentle electrical stimulation applied to your ear to help manage severe premenstrual mood changes or perimenopause symptoms. The device is worn for 2 hours daily, and researchers believe this type of stimulation may help balance hormones and reduce bothersome symptoms. The study will track how you feel before, during, and after using this treatment.
Many women experience severe mood swings, anxiety, or depression tied to their menstrual cycle or menopause, and current treatments don't work well for everyone. This trial is exploring whether stimulating specific nerves in the ear could be a safe, drug-free option to help manage these symptoms.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll use the ear stimulation device for about 2 hours daily for a set period—either four menstrual cycles (roughly 4 months) if you're in the mood study, or three months if you're in the perimenopause study. The first phase is a baseline where you track your symptoms without treatment; then you'll use the device during the treatment phase; and finally you'll have a follow-up phase to see how you feel afterward. You'll complete surveys online to report your symptoms and experiences throughout the study.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
United States
Sponsor
Texas Christian University
Collaborators
Spark Biomedical, Inc.
Enrollment target
~20 participants
Started
June 2026
Primary completion
March 2027
Age range
18 Years – 55 Years
Sex
Female only
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Sarah E Hill, PhD
Texas Christian University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.