Recruiting

Testing a new obesity treatment for safety and how the body processes it

Plain-English translation of NCT07693868 on ClinicalTrials.gov ↗ · Source last updated September 2026 · Translation generated August 2026 · How we translate trials

Read our Obesity research guide →

Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.

What is this trial?

This is a Phase 1 safety study of , a new experimental medication designed to treat obesity and related inflammation. Researchers are testing whether the medication is safe, how well people tolerate it, and how the body processes it. The study includes healthy adults as well as people living with obesity.

Obesity and related inflammatory conditions affect many people, and current treatment options are limited. This trial is designed to gather early safety data on this new treatment before it can be studied more broadly in larger patient populations.

Do you qualify?

You likely qualify if…

you are between 18 and 55 years old (or 18 to 65 if you're in the obesity-focused part of the study)
you have a healthy weight range, or if in the obesity part, a BMI of 30 or higher (or 27–29.9 with a high waist-to-height ratio)
you weigh at least 110 pounds
you are generally healthy with normal blood work, heart function, and vital signs
if you're in the obesity-focused part, you have mild to moderate inflammation markers in your blood

You likely don't qualify if…

you are allergic to any ingredients in the study medication or similar drugs
you have abnormal liver function tests, kidney function tests, or blood clotting markers
you are currently taking prescription medications or non-prescription medicines (with limited exceptions for pain relievers and vitamins)
you have received any vaccines within 14 days of screening
you have high levels of inflammation in your blood that fall outside the safe range for this study

What participation looks like

You will visit the research clinic multiple times over several weeks. Depending on which part of the study you join, you may receive a single dose of the medication, multiple doses over time, or a placebo (inactive pill). The researchers will monitor you closely with blood tests, heart function checks, and physical exams to assess safety and measure how your body processes the medication. Some participants will also be tested with the medication on a full stomach versus empty stomach to see if food affects how it works.

AI-generated summary from trial data · Aug 24, 2026 · Not medical advice

Trial locations(1 site)

Netherlands

ICON - location Groningen, Groningen