Plain-English translation of NCT07694076 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study investigates a new approach to treating depression by helping your brain learn to regulate itself. During two MRI scanning sessions, you'll receive real-time feedback showing your brain activity and practice mental exercises to control a key brain region involved in motivation and mood. Researchers want to see whether this training can improve how you feel and your ability to experience motivation and pleasure.
Many people with depression don't respond well to current treatments. This trial builds on earlier research showing that people can learn to control specific brain regions with practice and real-time feedback. The hope is that this targeted, personalized approach might help people whose depression hasn't improved with other treatments.
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You will attend two training sessions where you'll lie in an MRI scanner while viewing real-time images of your brain activity. Using guided mental strategies, you'll practice controlling activity in a specific brain region related to motivation and reward while receiving visual feedback. Between sessions, researchers will track changes in your mood and motivation to see whether the training helps.
AI-generated summary from trial data · Jul 14, 2026 · Not medical advice
United Kingdom