A minimally invasive procedure for posterior circulation stroke beyond 24 hours

Plain-English translation of NCT07699029 on ClinicalTrials.gov ↗ · Source last updated July 2026 · Translation generated August 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a minimally invasive procedure called endovascular treatment—where doctors use a catheter to reach and remove a blood clot in the back part of the brain. Researchers want to know if this procedure, done more than a day after a posterior circulation stroke, can help patients recover better when combined with standard medications. Currently, doctors are unsure whether this procedure is safe and effective this late after stroke onset.

Posterior circulation strokes (which affect the back of the brain) are serious, but most clot-removal procedures are only done within the first 24 hours after stroke symptoms start. This trial exists to find out whether performing this treatment later—between 24 hours and 14 days after stroke—can still help patients recover better and with fewer complications.

Do you qualify?

You likely qualify if…

you are 18 years old or older
you have had a posterior circulation stroke (in the basilar artery or vertebral arteries) confirmed by imaging
it has been between 24 hours and 14 days since your stroke started or your last moment of normal health
your stroke severity score is 4 or higher at the time of enrollment
you were independent and healthy before your stroke (no significant pre-existing disability)

You likely don't qualify if…

you have bleeding on your brain imaging (CT or MRI)
you have already undergone a clot-removal procedure for this stroke
you have severe bleeding disorders or are taking blood thinners with very high INR levels
you have extensive brain damage visible on imaging, or damage affecting both sides of the thalamus or the entire cerebellum with swelling
you are pregnant, have uncontrolled high blood pressure, or have other serious medical conditions that would make the procedure too risky

What participation looks like

If you join this trial, you will be randomly assigned to receive either the clot-removal procedure plus standard medical care, or standard medical care alone. The study will follow you for 90 days after your stroke, with assessments of your recovery and quality of life at that endpoint. You will need to attend follow-up visits and complete recovery assessments, but the exact schedule will depend on your treatment group and which hospital site enrolls you.

AI-generated summary from trial data · Aug 15, 2026 · Not medical advice

Trial locations(1 site)

China

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei