Plain-English translation of NCT07715188 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether low dose radiotherapy—a carefully controlled radiation treatment—can help reduce arthritis pain and improve how well your joints work. The study is for people whose arthritis hasn't gotten better with standard treatments, or who want to try a gentler option before considering surgery like joint replacement. Researchers will use several questionnaires to measure changes in your pain, daily function, and overall well-being.
Many people with arthritis don't get relief from the usual treatments and may be facing more aggressive options like joint surgery. This trial is exploring whether this treatment could offer a middle-ground option that's less invasive than surgery but more effective for people who've run out of other choices.
You likely qualify if…
You likely don't qualify if…
If you enroll, you'll receive one or two courses of low dose radiation therapy as your regular care. You'll then complete questionnaires about your pain, function, and well-being at the start of the study, at 3 months, and at 1 year. The questionnaires take about 10-15 minutes each and ask about your daily activities and how you're feeling. The entire study follows you for one year after your radiation treatment.
AI-generated summary from trial data · Aug 1, 2026 · Not medical advice
United States
Sponsor
Abramson Cancer Center at Penn Medicine
Enrollment target
~113 participants
Started
June 2026
Primary completion
June 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Marlowe Estioko, BS, MS
Abramson Cancer Center at Penn Medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.