Plain-English translation of NCT07725601 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new way to program vagus nerve stimulators (VNS devices) — small implanted devices that help control seizures — in people whose epilepsy hasn't responded well to medications. Researchers at Augusta University have developed a faster programming approach called "the Augusta Way" and want to compare it to the standard programming method. The study will follow patients for at least 2 years after their device is implanted to see if the new approach works better and is safe.
The way doctors program vagus nerve stimulators hasn't changed much in over 10 years, even though the technology has improved. This trial exists to create an updated treatment guide that doctors can use when adjusting these devices, and to find out whether programming them faster might help patients with drug-resistant epilepsy have better seizure control.
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If you join this trial, you will have a vagus nerve stimulator surgically implanted (if you don't already have one). You will then be randomly assigned to either the new "Augusta Way" programming method or standard programming. Your doctor will adjust your device settings over time, and you will have follow-up visits to check how well it's working and monitor for any side effects. You'll be followed for at least 24 months after implantation, with your seizure control and overall safety tracked throughout.
AI-generated summary from trial data · Aug 3, 2026 · Not medical advice
United States
Sponsor
Fernando Vale
Collaborators
Augusta University
Enrollment target
~80 participants
Started
August 2025
Primary completion
December 2028
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Brandy Quarles, MPH
Fernando Vale
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.