Plain-English translation of NCT07725783 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are investigating whether a protein called ProGRP in your blood can be used as an early warning sign of how your Ewing sarcoma is responding to treatment. By measuring this protein at specific times during your cancer care, doctors hope to better predict treatment success without waiting for imaging scans alone. This study won't change your actual treatment plan — it's purely observational to understand if this blood test could help guide future care.
Currently, doctors mainly rely on imaging scans (like X-rays or CT scans) to see if Ewing sarcoma is responding to chemotherapy, but these scans take time and may not catch early changes. A simple blood test could potentially give doctors faster feedback about whether treatment is working, allowing them to make adjustments sooner if needed.
You likely qualify if…
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You will receive your standard Ewing sarcoma treatment (chemotherapy, surgery, and/or radiation) as planned by your doctors. In addition, you'll have blood samples drawn at four key times: before chemotherapy starts, after a few cycles of chemotherapy, after completing chemotherapy but before surgery, and at your first follow-up visit after treatment. A lab will measure the ProGRP protein in these blood samples, and doctors will compare the results with your imaging scans to see if the blood test predicted treatment response.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
China
Sponsor
Peking University People's Hospital
Enrollment target
~100 participants
Started
September 2025
Primary completion
September 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
10 Years – 60 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lu Xie, M.D.
Peking University People's Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.