Plain-English translation of NCT07738003 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why autism happens and whether experiences during pregnancy and early childhood play a role. This study will follow over 7,000 pregnant women from the third trimester through their child's first 2.5 years, using a smartphone app called BabySteps to collect information about stress, daily life, and child development. By comparing children with autism, children with other developmental delays, and typically developing children, the team hopes to find ways to help children at risk.
Autism affects millions of families worldwide, but we don't fully understand why some children develop it. While genes are important, this study explores whether stress during pregnancy and how babies interact with caregivers early on also matter—and whether these factors work through changes in how our genes are switched on and off. Finding these connections could lead to new ways to help.
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If you're pregnant, you'll download the BabySteps app and use it to answer questions about stress, mood, and daily experiences from the third trimester through your child's first 2.5 years. Between 18 and 27 months, the app will screen for signs of autism or developmental delay. If your child is flagged, you'll be invited to bring them for a full evaluation at the University of Iowa Center for Disabilities and Development, either online or in person. Researchers will also collect DNA samples (a cheek swab or small blood sample) to look at how genes are working.
AI-generated summary from trial data · Aug 4, 2026 · Not medical advice
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