Recruiting

Brain stimulation and yoga for better thinking in psychosis

Plain-English translation of NCT07747181 on ClinicalTrials.gov ↗ · Source last updated August 2026 · Translation generated August 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This study is testing whether two treatments used together — transcranial direct current stimulation (tDCS), a gentle electrical brain stimulation, and yoga — can help improve memory, concentration, and thinking skills in people with psychosis. Researchers want to see if this combination helps with symptoms and quality of life, and also understand how it might work in the brain.

People with psychosis often experience problems with memory and concentration that can make work, school, and relationships difficult. Current treatments don't always fully address these thinking problems, so researchers are exploring whether this combination of brain stimulation and yoga might offer a new way to help.

Do you qualify?

You likely qualify if…

you are between 18 and 65 years old
you have been diagnosed with schizophrenia, another psychotic disorder, or delusional disorder with mild to moderate positive symptoms
you are able to understand the study and give informed consent
you speak Mandarin Chinese or Cantonese
you have done less than 10 hours of yoga or similar mind-body practices (like Tai Chi or meditation) in the past 3 months

You likely don't qualify if…

you have severe physical health problems such as recent heart attack, uncontrolled high blood pressure, or serious spine problems that would make exercise unsafe
you have a history of substance dependence or seizure disorders
you are pregnant
you have a history of intellectual disability, serious brain injury, or organic brain disease
you are taking benzodiazepines (you may still join the study, but would not be able to participate in certain brain imaging measurements)

What participation looks like

You would be randomly assigned to one of three groups: one receiving real brain stimulation plus yoga, one receiving sham (fake) stimulation plus yoga, or one on a waitlist. If assigned to an active treatment group, you would attend sessions where you receive the brain stimulation while practicing yoga. Throughout the study, you would have visits to measure your thinking skills, symptoms, and quality of life, and some participants may have special brain imaging scans to understand how the treatment works.

AI-generated summary from trial data · Aug 6, 2026 · Not medical advice

Trial locations(1 site)

Hong Kong

The Hong Kong Polytechnic University, Hung Hom, Kowloon