Comparing radiation therapy approaches for high-risk prostate cancer

This trial is testing two different ways of delivering radiation therapy to treat high-risk prostate cancer. Some men will receive a combination of two radiation approaches (brachytherapy boost plus SBRT), while others will receive SBRT alone. The goal is to find which approach best controls cancer while keeping side effects manageable and protecting quality of life.

Doctors want to find the most effective radiation therapy plan for men with aggressive prostate cancer—one that fights the cancer effectively without causing too many unwanted side effects. This trial will help determine whether combining two radiation methods works better than using one approach alone.