Plain-English translation of NCT07772167 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is investigating how the stomach sends signals to the brain in people who have functional dyspepsia (chronic stomach discomfort after eating) or anorexia nervosa (a serious eating disorder). By understanding these gut-brain connections better, researchers hope to develop more effective treatments for these conditions.
Many people with these digestive and eating disorders struggle with symptoms that don't improve with current treatments. By studying how the stomach and brain communicate, researchers may discover new ways to help people feel better.
You likely qualify if…
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As a participant, you would complete several visits involving medical interviews, questionnaires about your symptoms, and brain imaging scans (MRI) while your stomach's activity is monitored. During one of these scans, you would eat a small test meal containing pineapple to see how your stomach and brain respond. The study compares people with functional dyspepsia, people with anorexia nervosa, and healthy volunteers to identify differences in how their gut and brain communicate.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
United States
Sponsor
Massachusetts General Hospital
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrollment target
~150 participants
Started
March 2026
Primary completion
March 2030
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in August 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Caroline Adams
Massachusetts General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.