Plain-English translation of NCT07772752 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how often three antibiotics—sulfamethoxazole, ciprofloxacin, and amoxicillin—cause crystals to form in urine when given at higher doses. This is important because these crystals can sometimes damage the kidneys. This study will collect urine and blood samples from hospitalized patients receiving one of these medications to see who develops crystals and whether kidney problems follow.
High-dose antibiotics are necessary to treat serious infections, but they can sometimes cause crystals to form in the urinary system, which may lead to kidney injury. Doctors need better information about which patients are at risk so they can monitor them more carefully and prevent kidney damage.
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During your hospital stay, you will provide urine samples (typically your first morning urine) on specific days after starting the antibiotic—usually 2 to 4 times over the course of treatment. Your blood will also be tested on several occasions to check your kidney function. All samples will be collected as part of your normal hospital care, and your medical information will be reviewed. The entire study period depends on how long you take the antibiotic, typically ranging from a few days to two weeks.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
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