Plain-English translation of NCT07772869 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a simple uterine lavage—a gentle collection of fluid from inside the uterus—can help detect early signs of ovarian cancer in people who carry BRCA gene mutations. Researchers will analyze these fluid samples in the lab to look for molecular patterns that might indicate ovarian cancer risk. The goal is to develop a new screening tool that could help catch cancer earlier in high-risk patients.
People with BRCA mutations have a much higher lifetime risk of ovarian cancer, which is often caught too late. Researchers hope this fluid sample test could become an early warning system to catch cancer sooner, when it's easier to treat.
You likely qualify if…
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Before you have your planned risk-reduction surgery, you will undergo a uterine lavage—a quick, minimally invasive procedure where sterile fluid is gently placed into the uterus and then collected. This sample is then sent to the laboratory for molecular analysis to look for cancer-related markers. The procedure happens just once, at the time of your standard surgery, so it doesn't require extra visits.
AI-generated summary from trial data · Sep 16, 2026 · Not medical advice
United States
Sponsor
University of Washington
Enrollment target
~75 participants
Started
September 2026
Primary completion
June 2028
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in September 2026.
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Central contact
Intake Coordinators
Fred Hutch/University of Washington Cancer Consortium
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