Plain-English translation of NCT07780890 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are testing a new imaging technology called Brillouin hydration mapping that measures how much water is in your cornea (the clear front part of your eye). This technology could help detect eye diseases like dry eye, glaucoma, and corneal scarring earlier and more accurately than current methods. The study compares results from healthy people and people with different eye conditions.
Current eye exams can measure corneal thickness, but they cannot directly measure water content in the cornea. Abnormal water levels are a sign of many eye diseases. This new imaging technology could provide doctors with earlier warning signs of disease and better ways to monitor treatment.
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You will visit the research clinic at Massachusetts General Hospital for eye imaging using the Brillouin hydration mapping technology. The scan is non-invasive and painless—it uses light to measure water content in your cornea. The visit will likely take an hour or less. Depending on your role (healthy volunteer or patient), you may be asked to return for follow-up visits to track changes over time.
AI-generated summary from trial data · Aug 24, 2026 · Not medical advice
United States
Sponsor
Massachusetts General Hospital
Collaborators
Massachusetts Eye and Ear Infirmary, National Eye Institute (NEI)
Enrollment target
~90 participants
Started
August 2026
Primary completion
September 2027
Age range
20 Years – 79 Years
Last updated on clinicaltrials.gov in August 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Soyeon (Selina) Ahn, PhD
Massachusetts General Brigham
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.